Hamida, Fathin and Syafriana, Vilya Aktivitas Antibakteri Ekstrak Biji Anggur (Vitis vinifera L.) Terhadap Streptococcus mutans ATCC 31987. Jurnal Farmasi Etam.
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Abstract
Streptococcus mutans is one of the bacteria that cause dental caries. The antibiotics usually used for the therapy of this infection to inhibit bacterial growth. Polyphenol, which recommended as an antibacterial agent, is common secondary metabolites in grape seeds. 51 The purpose of this study is to know the activity of grape seed extract against Streptococcus mutans. The grape seeds were obtained from fresh fruits which bought from Pasar Induk, Kramat Jati, East Jakarta. The grape seed extract was obtained by the maceration method using ethyl acetate and 70% ethanol. The antibacterial activity test was carried out using the disk diffusion method on Mueller Hinton Agar media with a concentration of 5%, 10%, 20%, and 40%. The results showed that 70% ethanol extract of grape seeds had antibacterial activity at concentrations of 5%, 10%, 20%, and 40% with a value of 8.46 mm; 8.91 mm; 9.89 mm; and 11.04 mm respectively. The results of ethyl acetate extract also showed inhibitory activity at concentrations of 5%, 10%, 20%, and 40% with values of 7.72 mm; 8.50 mm; 9.64 mm; and 10.51 mm respectively. The inhibition of 70% ethanol extract of grape seed is greater than ethyl acetate extract. The results of the study can be used as reference for the potential development of grape seed as a medicinal or cosmedic cosmetic-medical) ingredient for treating dental caries.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | S.Si, M.Si FATHIN HAMIDA |
| Date Deposited: | 19 Nov 2024 03:06 |
| Last Modified: | 19 Nov 2024 03:06 |
| URI: | http://repository.istn.ac.id/id/eprint/11795 |
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