Antimicrobial Activity of Ethanol Extract of Akar Kaik-kaik (Uncaria cordata (Lour.) Merr.) Leaves Against Staphylococcus aureus, Escherichia coli, and Candida albicans

Syafriana, Vilya (2021) Antimicrobial Activity of Ethanol Extract of Akar Kaik-kaik (Uncaria cordata (Lour.) Merr.) Leaves Against Staphylococcus aureus, Escherichia coli, and Candida albicans. Advances in Biological Sciences Research, 14. pp. 540-546. ISSN 2468-5747

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Abstract

Akar kaik-kaik (Uncaria cordata) or known as hook vine is one of the medicinal plants whose leaves are used in traditional medicine as an antidiabetic by the people of Riau. Other than that, this plant also has potential as an antimicrobial agent due to the dominant of alkaloid content possessed by members of the genus Uncaria. This research aims to study the antimicrobial activity from the ethanol extract of akar kaik-kaik leaves against Staphylococcus aureus (Gram-positive bacteria), Escherichia coli (Gram-negative bacteria), and Candida albicans (yeast). The extraction was carried out using the maceration method and a solvent of 70% ethanol. The extract then tested for phytochemical screening to find out the secondary metabolite. After that, the extract was tested for antimicrobial activity. The test was done by Kirby-Bauer Method at Nutrient Agar (NA) for bacteria, and Sabouraud Dextrose Agar (SDA) for yeast. The extract contained alkaloid, saponin, and tannin according to the phytochemical analysis. The antimicrobial activity showed that the extract can inhibit the growth of S. aureus at a concentration of 10%, 20%, and 40% respectively about 6.91 ± 0.04 mm, 8.51 ± 0.14 mm, and 10.89 ± 1.09 mm. Meanwhile, the extract cannot inhibit the growth of E. coli and C. albicans.

Item Type:	Article
Subjects:	Q Science > QR Microbiology
Depositing User:	VILYA SYAFRIANA ISTN
Date Deposited:	05 Oct 2021 06:25
Last Modified:	05 Oct 2021 06:25
URI:	http://repository.istn.ac.id/id/eprint/2761

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